Tretinoin is the generic name for synthetic, first-generation all-trans-retinoic acid. Topical tretinoin first arrived on the dermatology scene in the 1960s. It is a prescription drug approved to treat acne, and in a few other FDA-approved products (which does not apply to our tretinoin products) as an adjunctive agent to treat fine facial wrinkling for patients who use comprehensive skincare and sun avoidance programs.

Available in multiple strengths and formulations by prescription only, Obagi tretinoin creams and gel work deep inside the skin to treat acne.